NMR Sensitivity
signal (s)
%
g
4
B
o
2
NB
1
g(
u
)/T
N
a
/ N
b
= e
D
E / kT
D
E
= g
h
B
o
/
2
p
D
E
≡
≡
B
o
g
g
1
H is ~ 64x as sensitive as
13
C and 1000x as sensitive as
15
N !
Consider that the natural abundance of
13
C is 1.1% and
15
N is 0.37%
relative sensitivity increases to ~6,400x and ~2.7x10
5
x !!