Instrumental Analysis

Content

Analytical Chemistry

You don’t need a course to tell you how to run an instrument

Questions to ask???

Off flavor cake mix (10%)

I.  Significant Figures

I.  Significant Figures

There is a difference - you

II.  Precision & Accuracy

"B."

Performance Characteristics: Figures of Merit

III. Types of Error

"B."

IV.  Statistical Treatment of Random Error (E_r)

A.  Normal Error Curve

A.  Normal Error Curve

Gaussian Distribution

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

B.  Statistics

Comparing Methods

Analytical Instruments

Data Domains

Slide 34

Slide 35

Slide 36

Slide 37

h(t) = a cos 2 pi freq. x time

Definitions

Definitions

Liner Plots

Slide 42

Signal-to-noise (S/N)

  Noise Reduction

Limit of detection

The limit of detection (LOD)

The limit of quantitation LOQ