CHEM 121. Chapters 17, 18 and 19.

Chapter 17.  Amines and Amides
1. Which functional group is found in amines?
     a. hydroxyl group   b.  aromatic   d. amino group   e. aldehyde group

2. Amines may be viewed as compounds that are substituted products of which inorganic compound?
   a. water  b.  ammonia  c. alcohol  d.  caboxylic acids

3. Amines are classified according to the number of alkyl or aryl groups directly attached to what atom?
   a.  nitrogen   b. sulfur    c.  oxygen    d.  hydrogen

4. How many R groups are directly attached to the nitrogen atom of a primary amine?
a. 1    b. 2   c  3    d.  4

5. How many R groups are directly attached to the nitrogen atom of a secondary amine?
a. 1    b. 2   c  3    d.  4
    
6. How many R groups are directly attached to the nitrogen atom of a tertiary amine?
    a. 1    b. 2   c  3    d.  4

7. What biological molecules contain the heterocyclic purines and pyrimidines?
   a. fatty acids  b. nucleic acids or DNA and RNA c. glycerol    d. glycerides

8. Which synthetic amine compounds stimulate the central nervous system and are often used in diet pills?
          a. nitrates b. serotonins c. epinephrines d. amphetamines e. barbiturates

9. Which synthetic amide compounds are used as sedatives and are also used as anticonvulsants?
a. amides b. serotonins c. epinephrines d. amphetamines e. barbiturates

10. What type of compound is produced when secondary amines react with nitrous acid?
a. nitric acid b. phenol nitrate c. nitrites d. nitrosoamines e. N,N-diethyamide

11. What is the name of the preservative in bacon and ham that may react with stomach acid to form nitrous acid?
         a. sodium benzoate b. nitrates c. benzoic acid d. sodium acetate e. citrate

12. A deficiency of which of the following amines has been linked to mental depression?
           a. acetylcholine b. choline c. serotonin d. cholesterol e. protein

13. Which of the following amines is involved in the on of nerve impulses that control the contraction of muscles?
            a. epinephrine b. alkaloid c. amide d. aminoedme e. acetylcholine

14. What disease results from a deficiency of dopamine?
                 a. Wilson's Disease          c. Parkinson's Disease     b. K-Factor Disease
                d. Niemann-Pick Disease e. Tay-Sachs Disease

15. Which of the following amines is involved in the breakdown of glycogen to glucose?
           a. epinephrine b. serotonin c. cephalin d. sphingomyelin e. cotisone

16. Which class of naturally occurring compounds contains one or more nitrogen heterocyclic rings and includes many
      compounds that have medicinal and physiological effects?
          a. analgesics b. alkaloids c. drugs d. nitrosoamines e. rarcinogens

17. What term is used for any drug that acts as a pain killer?
       a. analgesic b. alkaloids c. serotonins d. synthefics e. proamines

18. What term is used for any drug that causes lack of sensation in any part of the body or causes unconsciousness?
           a. analgesic b. anesthetic c. alkaloid d. proamine e. CNS

19. Which group of compounds is useful in causing a of the membranes that line the nasal passages?
         a. anesthetic b. analgesic c. alkaloid d. drugs e. decongestants

20. What subclass of amines contains at least one nitrogen atom in a ring structure?
         a. cyclic b. aliphatic c. saturated d. unsaturated e. heterocylic

21. How many carbon atoms are there in ethanamide?
           a. 1        b. 2         c. 3       d. 4       e. 5

22. What charge is usually found on a nitrogen atom that has four atoms directly attached to it?
            a. 0         b. +1          c. +2       d. -1      e. -2

23. Why is the bond between N and H in amines a polar bond?
        a. hydrogen is more electroneptive   c. nitrogen is more electronegative
        b. nitrogen is more electropositive   d. hydrogen is electrophilic
        e. nitrogen is electrophilic

24. What is the Chemical Abstracts name of the following compound?
 
        a. dimethylmethanamine   b. methylethanamine                 c. N-methylethanamine
        d. N-methylmethanamine e. N,N-dimethylmethanamine

25. What is the Chemical Abstracts name of the following compound?

        a. dimethylmethnamine          d. N- dimethylmethnamine
        b. N,N-diethylmethanamine  e. N,N-dimethylethanamine
        c. methylammoniumethane

26. In the laboratory, amines are prepared by the reduction of what two kinds of organic compounds?
         a. amides and amines b. nitrosoamines and amides  c. phenylamines and phenylnitro compounds
         d. amides and nitro compounds   e. amides and aldebydes

27. What is the I.U.P.A.C. name of the compound produced by the reduction of hexanamide?
         a. 1-hexanamine                d. methylpentanal
         b. 2-hexanamine               e. methylpentanamine
         c. hydroxylaminopentane

28. What is the common name of the following compound?

       a. N-methylethanamine                 d. timethylamine
       b. ethyhnethylamine                      e. N,N-methylethanamine
       c. N,N-dimethylmethanamine

29. What is the common name of the following compound?

        a. triethylamine                   d. N-methylethanamine
        b. N,N-diethylethanamine  e. N,N-dimethyletahnamine
        c. methylammoniumethane

30. What term best describes the following compound?
 
          a. primary amine b. secondary amine c. tertiary amine d. amide e. alkaloid

31. What product, in addition to a hydroxide ion, is formed when an amine reacts with water?
        a. hydronium ion                    d- quaternary ammonium salt
        b. alkylammonium ion             e. heterocyclic
        c. alkylammonium salt

32. What is the I.U.P.A.C. name of the following compound?

a. ethnamide b. acetamide c. methanamide d. formamide e. N-methanamide
33. What is the common name of the following compound?

        a. ethanamide b. acetamide c. methanamide d. formamide e. N-methanamide

Chapter 18. Carbohydrates

1. What is the simplest type of carbohydrate?
a.  monosaccharide    b.  disaccharide     c.  polysaccharide      d.  oligosaccharide

2. What is the most complex type of carbohydrate?
a.  monosaccharide    b.  disaccharide     c.  polysaccharide      d.  oligosaccharide

3. What substances can be either polyhydroxyaldehydes or polyhydroxyketones?
a.  carboxylic acids   b. carbohydrates or monosaccharides c. esters    d.  alcohols

4. If a substance is said to be levorotatory, what direction does it rotate plane polarized light.
a. clockwise   b. counterclockwise  c. parallel     d. vertical

5. What term describes an enantiomer that rotates plane polarized light in a clockwise direction?
a. dextrorotatory or   +    b. levorotatory or   - c. parallel     d. vertical

6. Whichch enantiomer of glyceraldehyde is represented in the following structure?

a. glyceraldehyde  b. L-glyceraldehyde  c. D-glyceraldehyde  d. L-glucose

7. The concentration of which monosaccharide foudd in the blood is regulated by the hormones insulin and glucagon?
a.  mannose     b.  glucose   c. fructose    d. sucrose    e. galactose

8. To what class of carbonyl containing compounds does glucose belong?
a. ketone    b.  carboxylic acid   c.  aldehydes    d.   esters   e. acid anhydrides

9. Which isomer of the ring configuration of D-glucose has the -OH at carbon-1 below the ring.
a.     b. b    c.      d.  d

10. What type of rompound is produced in the reaction between an alcohol and a ketone?
a. hemiacetal    b.    ketal      c.    acetal        d. hemiketal

11. Which carbohydrate is found in RNA?
  a.  glucose or D-glucose    b.  fructose or D-fructose     c. ribose or D-ribose   d. deoxyribose or D-oxyribose

12. Which carbohydrate is found in DNA?
  a.  glucose or D-glucose    b.  fructose or D-fructose     c. ribose or D-ribose   d. deoxyribose or D-oxyribose

13. What reaction can convert a ketose into an aldoses?
a. esterification    b. hydrolysis  c.  enediol reaction   d.  saponification

14. The following structure is the enediol form that would exist between D-glucose and what other sugar?

a. D-glucose     b. D-galactose   c.  D-mannose   d.   D-fructose   e.  D-glyceraldehyde

15. Which of the following types of bonds holds one monosaccharide to the next one in a polysaccharide.
          a. glycosidic       b. carbonyl         c. diol         d. ester        e. aldehyde

16. What functional group, in addition to the hydroxyl group, characteterizes all monosaccharides?
            a. ester        b. carbonyl          c. alkene        d. aldehyde        e. diol

17. Which of the following is the molecular formula of fiuctose?
          a. C6H12O  b. C6H12O6    c. C6H10O6     d. C5 H10O        e. C9H18O9

18. What is the term for a pair of  D- and L-isomers?
         a. geometric isomers        b. chiral         c. enantiomers         d. trans          e. polar

19. What is the term for two molecules that can exist as two nonsuperimposable mirror-image forms?
          a. dextrorotatory        b. straight         c. trans -cis        d. enantiomers         e. anomers

20. How would we designate an enantiomer that rotates plane polarized light in a clockwise direction?
          a. +         b. -          c.     D-        d. L-           e. chiral

21. which enantiomer of glyceraldehyde is represented in the following structure?


              a. trans          b. cis          c. neutral        d. D-       e. L-

22. Which of the following is the simplest aldose?
           a. glucose          b. fructose      c. mannose       d. dihydroxyaldehyde           e. glyceraldehyde

23. To what class of carbonyl containing compounds does fructose belong?
          a. alcohol           b. ketone       c. aldehyde        d. diol         e. carboxylic acid

24. What is the position of the -OH at carbon-1 in the b-D-glucose?
         a. above the ring               c. to the right of carbon-1
         b. below the ring               d. to the left of carbon-1

25.Which form of D-glucose in the ring configuration has the -OH at carbon-1 above the ring
    a. hemiketal            b. hemiacetal       c.b        d. a          e. g

26. On which specific carbon atom of galactose are the hydroxyl group and hydrogen atom the reverse of what is found on the same carbon atom in glucose?
       a. 1       b. 2       C. 3       d. 4      e. 5

27. Glucose and what other monosaccharide combine to form lactose?
           a. glucose          b. mannose        c. fructose        d. sucrose      e. galactose

28. which of the following is a nonreducing disaccharide?
            a. mannose         b. maltose        c. sucrose         d. lactose       e. ribose

29. Which of the following is the principal carbohydrate in milk?
            a. glucose       b. maltose         c. mannose       d. lactose         e. sucrose

30. What polysaccharide found in animls has a structure  very similar to amylopectin?
                   a. glucose          b. glycogen        c. starch         d. amylose         e. cellulose

31. Which organ releases glucose, produred by the degradation of glycogen, into the bloodstream?
        a. muscle         b. kidney         c. gall bladder       d. fat cells        e. liver

32. The absence of the enzyme lactase is responsible for which of the ' following conditions?
          a. galactosemia       b. glucosuria       c. diabetes       d. lactose intolerance

33. What is the name of the disaccharide most widely used as a sweetener?
               a. glucose      b. fructose       c. sucrose         d. lactose         e. maltose

34. Which of the following polysaccharides cannot be digested by humans?
             a. glycogen      b. cellulose        c. amylose        d. amylopectin      e. sucrose

35. What is the product in the reaction between the aldehyde portion of a glucose molecule and the C-5 hydroxyl group?
          a. intramolecular hemiketal         d. intermolecular hemiacetal
          b. intermolecular hemiketal         e. stereoisomer
          c. intramolecular hen3iacetal

36. Which of the following is the simplest carbohydrate?
         a. glucose         b. fructose       c. galactose        d. glyceraldehyde     e. ribose

37. Which of the following is NOT a name for the most important monosaccharide in the human body?
       a. glucose       b. milk sugar          c. dextrose        d. blood sugar

38. One complex carbohydrate in a healthy diet is cellulose. What is another one?
        a. starch        b. glucose         c. lactose         d. monosaccharides       e. sucrose

39. What is the term for carbohydrates consisting of two to ten monosaccharide units bonded together?
        a. disaccharide         b. polysaccharide         c. ohgosaccharide         d. aldose        e. ketose
 

Chapter 19. Lipids and Their Biochemical Functions

1. Which class of biological compounds of varying chemical composition is grouped together on the basis of the solubility of these compounds?
a. proteins b. lipids c. carbohydrates   d.sugars

2. At room temperature, what is the physical state of saturated fatty acids containing ten or more carbon atoms?
a. gas    b. liquid   c.  solids  d. solution
 
3. Name the fatty acid that has the formula C17H35COOH.

a.  caproic acid    b. palmitic acid   c. stearic acid  d. oleic acid   e. arachidonic acid
 
4. Name the product in the following reaction.
a.  caproic acid    b. palmitic acid   c. stearic acid  d. oleic acid   e. arachidonic acid
 
5. Which of the following is not an eicosanoids.

a. prostaglandins    b. leukotrienes   c.  thromoboxanes  d. estrogen

6. What response is caused by the Prostaglandins produced in the kidneys?
a. dilation of renal blood vessels  b.inhibition of platelet formation  c. simulation of platelet aggregation
d. inhibition of gastric secretion.

7. Write the I.U.P.A.C. name of the product of the following reaction:
a. methanal    b.   propanal    c. ethanal  d. butanal

8. Hydrogenation is used in the food industry to convert polyunsaturated vegetable oils into what?
a.  caboxylic acid    b.  aldehyde      c. saturated solid fats     d.  alkane      e.  alcohol


9.  Name the two essential fatty acids.
a. palmitic acid and stearic acid   b.  linoleic acid and linolenic acid
c. butric acid and valeric acid      d. capric acid and myristic acid

10. Which of following is not an eicosanoids.
a. Prostaglandins b.  leukotrienes c. thromoboxanes d. estrogen

11.  What products are formed from the complete hydrolysis of a triglyceride?

a. glycerol     b. fatty acids     c.   glycerol and 3 fatty acids    d. alcohol

12. What functional group characterizes the phospholipids?
a. hemiacetal    b.    ketal      c. phosphoryl group  d. alcohol     e. aldehyde

13. What nitrogen-containing alcohol is found m the sphmgohpids?
Answer: sphingosine
a.  glycerol   b. fatty acid  c. sphingosine   d. phosphoryl group   e. heme

14. Which class of biological compounds is insoluble in water but soluble in nonpolar organic compounds?
         a. proteins b. enzymes c. lipids d. fats e. triglycerides

15. What type of lipid is the most common storage form in the human body?
      a. wax b. lipoprotein c. fatty acid d. triglyceride e. saturated

16. Which lipid hormones allow tissues of the body to communicate with one another?
       a. steroids b. lipoproteins c. enzymes d. arachidonates e. Prostaglandins

17. Which lipids are long-chain monocarboxyhc acids?
        a. triglycerides b. waxes c. fatty acids d. prostaglmdins e. enzymes

18. Fatty acids generally contain how many carbon atoms?
         a. 12 b. 8 c. 6 d. an odd number e. an even number

19. Which kind of fatty acid contains only single bonds in its R groups
         a. saturated b. unsaturated c. even d. odd e. prostaglandins

20. Which kind of fatty acid contains at least one double bond in its R group?
           a. saturated b. unsaturated c. even d. odd e. steroids

21. The formula CnH2n+1COOH would represent which type of fatty acid?
             a. saturated b. unsaturated c. even d. odd c- protaglandins

22. What happens to the melting points of the fatty acids as the number of double
bonds in their R group increases?
              a. doubles b. reduced in half c. decreases d. increases e. stays the same

23. What process may be used to convert an unsaturated fatty acid into a saturated fatty acid?
                 a. addition b. combustion c. esterification d. hydrolysis e. hydrogenation

24. What is the product of the complete hydrogenation of linoleic acid?
               a. linolenic acid b. wax c. arachidonic acid d. an ester e. stearic acid

25. What highly unsaturated fatty acid is synthesized from the fatty acid linoleic acid in the body?
               a. stearic acid b. linolenic acid c. palmitoleic acid d. arachidonic acid

26. Which of the following hormone-like molecules are NOT produced from arachidonic acid?
             a. Prostaglandins b. eirosanoids c. leukotrienes d. thromoboxanes e. steroids

27. Which kind of eicosanoids is thought to promote certain aspects of the inflammatory response?
                a. leukotrienes b. prostaglandins c. tbromoboxanes d. steroids e. fatty acids

28. Aspirin blocks the synthesis of which of the following eicosanoids?
              a. leukotrienes b. enzymes c. thromoboxanes d, phospholipids e. prostaglandins

29. There is strong evidence that painful menstruation may be the result of an excess
of which of the following eicosanoids?
             a. leukotrienes b. thromoboxanes c. prostaglandins d. steroids e. phospholipids

30. Cylooxygenase catalyzes the conversion of arachidonate into PGH2. What drug inhibits this enzyme?
             a. testosterone b. aspirin c. progesterone d. norlutin e. cortisone

31. What is the major energy storage form found in fat cells?
              a. waxes b. phospholipids c. acetylcholines d. triglycerides e. low density lipids

32. What is another name for phosphatidylcholine?
               a. phospholipid-D b. sphingosine c. cholesterol d. lecithin e. chylomicron

33. Which steroid is responsible for both the successful initiation and completion of pregnancy?
            a. cholesterol b. sphingosine c. chylomicron d. progesterone e. cortisone

34. Identify the following structure:

         a. monoglyceride b. diglyceride c. triglyceride d. glycerol e. acid

35. What is the general term for lipids synthesized from isoprene units?
a. cholesterol b. waxes c. chylomicrons d. terpenes e. high density lipoproteins

 


Frshmen Course Material
Chemistry Program, College of Engineering and Science
This page was last modified on January 24, 2000
This page was last updated January 24, 2000  by upali@chem.latech.edu alias Upali Siriwardane, General Chemistry, Chemistry Program, Louisiana Tech University, Ruston , LA 71272, USA.
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